GeneSight® Testing: A Comprehensive Tool for Guiding Substance Use and Mental Health Treatment

Finding the right mental health medication can be frustrating. GeneSight testing uses your DNA to help your doctor choose medications that are more likely to work for you—reducing trial and error and helping you feel better, faster.

Dr. Rostislav Ignatov
Clinically Reviewed
Dr. Rostislav Ignatov MD
Chief Medical Officer​​

What is GeneSight Testing?

Treating mental health concerns is not a one-size fits all process, and medications that work well for one person may not work well for you. 

GeneSight testing offers a clear, confident path forward in treatment through a swab of a cheek

Is GeneSight testing accurate?

Genesight Testing being conducted by swabbing the patients cheeks

Benefits of GeneSight Testing

Taking a med that doesn’t react well with your body can make symptoms worse, set you back, and put you at risk for relapse. 

GeneSight testing makes the road to relief easier.

Who Should Consider GeneSight Testing?

If you’re in treatment and also managing your mental health, you’re not alone . Nearly half of people who struggle with substance use also have co-occurring mental health conditions like:

If you’re being treated for any of these conditions and you feel like your medication isn’t helping, or even making these worse, GeneSight testing might be for you.

You should consider GeneSight testing if:

What Medications Does GeneSight Test For?

By taking the uncertainty out of finding a med that works, you can be on your way to feeling more like yourself again. 

GeneSight testing covers a wide variety of commonly prescribed mental health medications including:

How Long Does GeneSight Testing Take?

The GeneSight test is a quick, easy, and non-invasive cheek swab that takes five minutes or less to complete

After the sample is taken, the test is sent to a certified lab for analysis.

In just 2-5 business days, the results of the test are made available to your doctor. 

Your doctor will look over your results and consult with you on treatment plan options that make the most sense for you.

How Do I Read My Results?

GeneSight test results are easy to read and organize medications into three color-coded categories:  

GeneSight logo above the text 'How Do I Read My Results?' followed by the explanation: 'Your GeneSight test results will also provide metabolism insights that can help inform your doctor’s medication recommendations.'
Green box labeled 'Use as Directed' listing medications: desipramine (Norpramin), desvenlafaxine (Pristiq), levomilnacipran (Fetzima), nortriptyline (Pamelor), trazodone (Desyrel), vilazodone (Viibryd), vortioxetine (Trintellix), duloxetine (Cymbalta), mitazapine (Remeron), with note: 'Likely to be an effective treatment option.'
Yellow box labeled 'Moderate Gene-drug Interaction' listing medications: venlafaxine (Effexor), selegiline (Emsam), fluoxetine (Prozac), clomipramine (Anafranil), fluvoxamine (Luvox), with note: 'May require adjustments to dosage or closer supervision.
Red box labeled 'Significant Gene-drug Interaction' listing medications: bupropion (Wellbutrin), amitriptyline (Elavil), paroxetine (Paxil), escitalopram (Lexapro), sertraline (Zoloft), imipramine (Tofranil), citalopram (Celexa), doxepin (Sinequan), with note: 'Use with increased caution and monitoring. Usage may not be effective and may cause negative side effects.
A graphic explaining how to interpret GeneSight test results, with a heading “How Do I Read My Results?” and a note that these results provide metabolism insights to inform medication recommendations. The graphic is split into three color-coded columns: Green column (Use as Directed): These medications are likely to be an effective treatment option. List of medications: desipramine (Norpramin®) desvenlafaxine (Pristiq®) levomilnacipran (Fetzima®) nortriptyline (Pamelor®) trazodone (Desyrel®) vilazodone (Viibryd®) vortioxetine (Trintellix®) duloxetine (Cymbalta®) mitazapine (Remeron®) Yellow column (Moderate Gene-drug Interaction): These medications may require adjustments to dosage or closer supervision. List of medications: venlafaxine (Effexor®) selegiline (Emsam®) fluoxetine (Prozac®) clomipramine (Anafranil®) fluvoxamine (Luvox®) Red column (Significant Gene-drug Interaction): These medications should be used with increased caution and monitoring, as usage may not be effective and could cause negative side effects. List of medications: bupropion (Wellbutrin®) amitriptyline (Elavil®) paroxetine (Paxil®) escitalopram (Lexapro®) sertraline (Zoloft®) imipramine (Tofranil®) citalopram (Celexa®) doxepin (Sinequan®) Each column emphasizes the recommended level of caution for medication use based on an individual’s genetic profile.

Your GeneSight test results will also provide insights on your metabolism that can help inform your doctor’s medication and dosage recommendations. 

For each medication, the test results tell you whether you process it too fast or too slow and how that may affect the dosage you need. 

Is GeneSight Covered By Insurance?

Your GeneSight test results will also provide insights on your metabolism that can help inform your doctor’s medication and dosage recommendations. 

For each medication, the test results tell you whether you process it too fast or too slow and how that may affect the dosage you need. 

Good news—GeneSight testing is covered by Medicare and Medicaid, so most people under those plans don’t have to pay anything out of pocket. 

If your plan is under a private insurance company, there’s a good chance that GeneSight testing will be fully or partially covered.

Where To Get GeneSight Testing

At The Haven Detox, your treatment is never one-size-fits-all. That’s why we offer GeneSight testing along with a full spectrum of therapies and medical care to provide you with treatment that works. 

If you’re seeking treatment that is backed by real science, grounded in compassion, and tailored to meet your unique needs, contact us today.

A banner confirming that The Haven Detox is a registered GeneSight Provider

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