Who Created Methamphetamine: Explore The Origins

Dr. Rostislav Ignatov MD
Chief Medical Officer​​

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Introduction To Methamphetamine

Methamphetamine, often called meth, is a powerful drug that affects the brain and body. It comes in several forms, including a white powder or crystalline form. People usually take meth by snorting, smoking, or injecting it. Meth is known for giving a quick, intense feeling of euphoria or a “rush.” It also commonly goes by names like crystal meth, speed, ice, and glass.

Using meth can lead to serious health problems. It can increase heart rate, blood pressure, and body temperature. Long-term use can damage the brain, leading to memory loss and violent behavior. In addition, meth use can cause severe dental issues, known as “meth mouth,” and extreme weight loss.

Methamphetamine is highly addictive, meaning users can develop a strong dependence on it. Treatment for meth addiction often requires medical help and support from family members and friends. It is essential to seek help if you or someone you know is struggling with meth addiction.

Early Discoveries Of Methamphetamine

The history of methamphetamine dates back to the late 19th and early 20th centuries. Various scientists and researchers made significant contributions during this period, paving the way for its development and use.

Discovery Of Amphetamine

The story begins with amphetamine, the parent compound of methamphetamine. In 1887, Romanian chemist Lazăr Edeleanu first synthesized amphetamine in Germany. He named it “phenylisopropylamine.” Although Edeleanu’s discovery didn’t initially attract much attention, it laid the groundwork for future research. The stimulating effects of amphetamine use on the central nervous system would later be recognized and explored, leading to its medical and recreational use.

Nagai Nagayoshi: The Pioneer

Nagai Nagayoshi, a Japanese chemist, played a significant role in the history of methamphetamine. In 1893, he was the first to synthesize methamphetamine from ephedrine, a natural stimulant found in certain plants. Nagayoshi’s work was groundbreaking and set the stage for future research and development of methamphetamine. His discovery highlighted the potential for synthetic stimulants to impact medicine and society significantly.

Other Notable Contributors

Several other scientists made important contributions to methamphetamine’s history. In 1919, Japanese pharmacologist Akira Ogata improved Nagai’s synthesis method, making meth easier to produce. During World War II, the drug gained popularity as a stimulant for soldiers for its ability to combat fatigue. Notable figures like Dr. Gordon Alles and Dr. Fritz Hauschild also contributed to the study and development of this powerful drug.

Key Takeaways

Methamphetamine was first synthesized in the late 19th century, setting the stage for its later developments. This article covers:

  • During World War II, meth was used by military forces to enhance performance, leading to its widespread use and later abuse.
  • Illegal meth production surged with the rise of underground labs and criminal organizations, leading to its global spread.
  • Today, methamphetamine is an illicit drug, and its production methods are more sophisticated, posing serious challenges.

World War II And Methamphetamine

Methamphetamine played a significant role during World War II, influencing both military strategy and post-war society. Its use by various military forces and its aftermath reveal the profound impact of this powerful stimulant.

German Military Use
During World War II, the German military used methamphetamine extensively. Known as “Pervitin,” it was given to soldiers to boost their energy, endurance, and alertness. This drug enabled troops to stay awake for extended periods, enhancing their combat effectiveness. The widespread use of methamphetamine among German soldiers highlighted its potential to enhance performance despite the severe side effects that many experienced.
Japanese Military Use
The Japanese military also made extensive use of methamphetamine during World War II. The drug was distributed under the brand name Philopon. Japanese soldiers used it to stay awake and fight fatigue, similar to the German experience. Methamphetamine helped the Japanese military maintain their combat effectiveness in challenging conditions, particularly in the Pacific Theater, where long and grueling engagements were common.
Post-War Proliferation
After the war, the use of methamphetamine spread beyond the military. Soldiers returning home brought knowledge of the drug with them, leading to its increased availability and abuse in civilian populations. In the post-war years, methamphetamine was marketed for various medical conditions, further increasing its use. However, the adverse effects became apparent, leading to tighter regulations and eventual bans in many countries.

Methamphetamine Evolution and Impact

Originally introduced in the 1950s as a prescription drug for conditions like ADHD and obesity, methamphetamine gained popularity for its stimulant effects. Promoted by pharmaceutical companies under names like Desoxyn, it was widely prescribed until its addictive potential became clear. By the 1970s, mounting health concerns led to stricter legal controls and classification as a controlled substance, limiting its legitimate use and prompting a shift toward illegal production.

 

As legal restrictions tightened, underground meth labs emerged, using hazardous chemicals and unsupervised methods to meet growing demand. Criminal organizations quickly capitalized on this shift, establishing extensive networks for manufacturing and distributing methamphetamine. Over time, illicit production spread globally, adapting to enforcement efforts and creating a widespread public health issue fueled by international trafficking and organized crime.

 

Today, methamphetamine remains a serious threat, classified as a Schedule II controlled substance due to its high abuse potential. While production methods have grown more advanced—often involving pseudoephedrine from cold medications—the drug continues to devastate users with physical and mental health issues. Its social impact is equally severe, contributing to crime, broken families, and economic hardship, necessitating ongoing efforts in prevention, treatment, and law enforcement.

Frequently Asked Questions

Navigating the journey to recovery can bring up many questions. Below are some of the most commonly asked questions about our services. If you need more information or have additional questions, we are only a phone call away.

Methamphetamine was created in the early 20th century for medical purposes. Scientists aimed to develop a drug to help people with breathing problems like asthma. It was also used to treat attention deficit disorders and narcolepsy, a condition where people suddenly fall asleep.

During World War II, soldiers used it to stay awake and alert. However, over time, the harmful effects and potential for addiction became clear, leading to its more restricted use. Today, methamphetamine is mainly known for its dangerous impact on health and society rather than its original medical purposes.

Methamphetamine was first developed in 1893 by a Japanese chemist named Nagai Nagayoshi. He created it by modifying ephedrine, a compound found in a plant. This early form of methamphetamine was initially used to treat breathing problems and was sold under various brand names.

In 1919, another chemist named Akira Ogata improved the method for making methamphetamine, making it more effective. It wasn’t until the 1930s, however, that methamphetamine began to be used widely, including by the military during the Second World War, to keep soldiers awake and alert.

Despite its medical uses, its addictive nature became a serious issue later on.

Methamphetamine use has changed significantly over time. Initially, it was used medically to treat conditions like asthma and narcolepsy and was even used by soldiers during World War II to stay awake. In the 1950s and 1960s, it was available as a prescription drug for weight loss and depression.

However, by the 1970s, the dangers of addiction and health problems became evident, leading to strict regulations. Today, meth is mainly known for its illegal use and harmful effects. Its abuse has led to severe health issues, including drug use disorders, mental health problems, and social consequences.

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